DPABH-20169

antibody from Creative Diagnostics

Targeting: COPS5 CSN5, JAB1, MOV-34, SGN5

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-20169

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-20169, RRID:AB_2503665

Product name

Rabbit Anti-Human COPS5 Polyclonal antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL