Tissue expression
Cell line expression
Protein structure
NANS
N-acetylneuraminate synthaseSAS
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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LSBio | ![]() |
Monoclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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