APR03858G

antibody from Leading Biology

Targeting: IL13 ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03858G

Provider

Leading Biology

Product name

IL13 Antibody (C-term)

Antibody type

Polyclonal

Description

This gene encodes an immunoregulatory cytokine producedprimarily by activated Th2 cells. This cytokine is involved inseveral stages of B-cell maturation and differentiation. Itup-regulates CD23 and MHC class II expression, and promotes IgEisotype switching of B cells. This cytokine down-regulatesmacrophage activity, thereby inhibits the production ofpro-inflammatory cytokines and chemokines. This cytokine is foundto be critical to the pathogenesis of allergen-induced asthma butoperates through mechanisms independent of IgE and eosinophils.This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster onchromosome 5q, with this gene particularly close to IL4. [providedby RefSeq].

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.