AMM03937G

antibody from Leading Biology
Targeting: PRKCA PKCA, PKCĪ±
Provider product page for AMM03937G
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
AMM03937G - Provider product page
Provider
Leading Biology
Product name
PRKCA Antibody (monoclonal) (M01)
Antibody type
Monoclonal
Description
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
2F11
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
PRKCA protein structure - AMM03937G shown in red.