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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN1580411 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- affinity purified antibody
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2A7
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term or -20°C long term.
- Handling
- Avoid repeated freezing and thawing.
Submitted references alpha-Synuclein locus triplication causes Parkinson's disease.
Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K
Science (New York, N.Y.) 2003 Oct 31;302(5646):841
Science (New York, N.Y.) 2003 Oct 31;302(5646):841
Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.
Culvenor JG, McLean CA, Cutt S, Campbell BC, Maher F, Jäkälä P, Hartmann T, Beyreuther K, Masters CL, Li QX
The American journal of pathology 1999 Oct;155(4):1173-81
The American journal of pathology 1999 Oct;155(4):1173-81
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
Krüger R, Kuhn W, Müller T, Woitalla D, Graeber M, Kösel S, Przuntek H, Epplen JT, Schöls L, Riess O
Nature genetics 1998 Feb;18(2):106-8
Nature genetics 1998 Feb;18(2):106-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Blots of ABIN1580411 on recombinant ?-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Mixed neuron-glial cultures stained with ABIN1580411, our monoclonal antibody to ?-synuclein (red) and chicken polyclonal antibody to MAP2 CPCA-MAP2 (green). The ?-synuclein antibody stains vesicular structures the perikarya and processes of the neurons in this image. Note that some of the neuronal perikarya contain much more ?-synuclein than others. The blue channel shows the localization of DNA.
