BS4361

antibody from Bioworld Technology, Inc
Targeting: SNCA NACP, PARK1, PARK4, PD1
Provider product page for BS4361
Western blot
Immunohistochemistry

Antibody data

Product number
BS4361 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Synuclein Ï« (phospho S129) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 100-150 of Human Synuclein-Ï«.
Description
The synuclein family members, including Ï«-synuclein (also designated NACP for non-ÉÇ Amyloid component) and ÉÇ-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. Ï«-synuclein is localized to neuronal cell bodies and synapses. Ï«-synuclein was first identified as a component of Alzheimer£ªs disease amyloid plaques. Abnormal platelet function in Alzheimer£ªs disease has been demonstrated. During megakaryocytic differentiation Ï«-synuclein has been found to be upregulated, while ÉÇ-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of Ï«-synuclein has been found in patients with early onset Parkinson£ªs disease.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SNCA protein structure - BS4361 shown in red.