Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- R-060-100 - Provider product page
- Provider
- Biosensis Pty Ltd
- Proper citation
- Biosensis Cat#R-060-100, RRID:AB_2492699
- Product name
- Rabbit antibody to pan synuclein: whole serum
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- A synthetic peptide (AKEGVVAAAEKTKQGV) as a consensus part of human alpha-, beta-, and gamma synuclein proteins conjugated to diphteria toxoid has been used as the immunogen.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Antigen sequence
AKEGVVAAAEKTKQGV
- Vial size
- 100 µl
- Storage
- Lyophilised. After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- Handling
- Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Submitted references The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties.
Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.
Alpha- and gamma-synuclein proteins are present in cerebrospinal fluid and are increased in aged subjects with neurodegenerative and vascular changes.
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
Näsström T, Fagerqvist T, Barbu M, Karlsson M, Nikolajeff F, Kasrayan A, Ekberg M, Lannfelt L, Ingelsson M, Bergström J
Free radical biology & medicine 2011 Feb 1;50(3):428-37
Free radical biology & medicine 2011 Feb 1;50(3):428-37
Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.
Ulusoy A, Febbraro F, Jensen PH, Kirik D, Romero-Ramos M
The European journal of neuroscience 2010 Aug;32(3):409-22
The European journal of neuroscience 2010 Aug;32(3):409-22
Alpha- and gamma-synuclein proteins are present in cerebrospinal fluid and are increased in aged subjects with neurodegenerative and vascular changes.
Mukaetova-Ladinska EB, Milne J, Andras A, Abdel-All Z, Cerejeira J, Greally E, Robson J, Jaros E, Perry R, McKeith IG, Brayne C, Xuereb J, Cleghorn A, Doherty J, McIntosh G, Milton I
Dementia and geriatric cognitive disorders 2008;26(1):32-42
Dementia and geriatric cognitive disorders 2008;26(1):32-42
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
Eslamboli A, Romero-Ramos M, Burger C, Bjorklund T, Muzyczka N, Mandel RJ, Baker H, Ridley RM, Kirik D
Brain : a journal of neurology 2007 Mar;130(Pt 3):799-815
Brain : a journal of neurology 2007 Mar;130(Pt 3):799-815
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