Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
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- Product number
- ALX-804-258-LC05 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-258-LC05, RRID:AB_11180660
- Product name
- _-Synuclein (human) monoclonal antibody (15G7)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 15G7
- Vial size
- 0.5 ml
- Storage
- -20°C
- Handling
- Aliquot diluted antibody into smaller volumes prior to freezing. Avoid freeze/thaw cycles.
Submitted references High-content analysis of α-synuclein aggregation and cell death in a cellular model of Parkinson's disease.
Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype.
Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease.
Intact olfaction in a mouse model of multiple system atrophy.
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
Bladder dysfunction in a transgenic mouse model of multiple system atrophy.
Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway.
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Clinicopathologic study of a SNCA gene duplication patient with Parkinson disease and dementia.
Alpha-synuclein overexpression increases cytosolic catecholamine concentration.
Lipid rafts mediate the synaptic localization of alpha-synuclein.
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies.
Macchi F, Deleersnijder A, Van den Haute C, Munck S, Pottel H, Michiels A, Debyser Z, Gerard M, Baekelandt V
Journal of neuroscience methods 2016 Mar 1;261:117-27
Journal of neuroscience methods 2016 Mar 1;261:117-27
Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype.
Kuzdas-Wood D, Irschick R, Theurl M, Malsch P, Mair N, Mantinger C, Wanschitz J, Klimaschewski L, Poewe W, Stefanova N, Wenning GK
PloS one 2015;10(10):e0136575
PloS one 2015;10(10):e0136575
Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease.
Paumier KL, Sukoff Rizzo SJ, Berger Z, Chen Y, Gonzales C, Kaftan E, Li L, Lotarski S, Monaghan M, Shen W, Stolyar P, Vasilyev D, Zaleska M, D Hirst W, Dunlop J
PloS one 2013;8(8):e70274
PloS one 2013;8(8):e70274
Intact olfaction in a mouse model of multiple system atrophy.
Krismer F, Wenning GK, Li Y, Poewe W, Stefanova N
PloS one 2013;8(5):e64625
PloS one 2013;8(5):e64625
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
Fellner L, Irschick R, Schanda K, Reindl M, Klimaschewski L, Poewe W, Wenning GK, Stefanova N
Glia 2013 Mar;61(3):349-60
Glia 2013 Mar;61(3):349-60
Bladder dysfunction in a transgenic mouse model of multiple system atrophy.
Boudes M, Uvin P, Pinto S, Voets T, Fowler CJ, Wenning GK, De Ridder D, Stefanova N
Movement disorders : official journal of the Movement Disorder Society 2013 Mar;28(3):347-55
Movement disorders : official journal of the Movement Disorder Society 2013 Mar;28(3):347-55
Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway.
Klucken J, Poehler AM, Ebrahimi-Fakhari D, Schneider J, Nuber S, Rockenstein E, Schlötzer-Schrehardt U, Hyman BT, McLean PJ, Masliah E, Winkler J
Autophagy 2012 May 1;8(5):754-66
Autophagy 2012 May 1;8(5):754-66
Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH
Neuron 2010 Jan 14;65(1):66-79
Neuron 2010 Jan 14;65(1):66-79
Clinicopathologic study of a SNCA gene duplication patient with Parkinson disease and dementia.
Obi T, Nishioka K, Ross OA, Terada T, Yamazaki K, Sugiura A, Takanashi M, Mizoguchi K, Mori H, Mizuno Y, Hattori N
Neurology 2008 Jan 15;70(3):238-41
Neurology 2008 Jan 15;70(3):238-41
Alpha-synuclein overexpression increases cytosolic catecholamine concentration.
Mosharov EV, Staal RG, Bové J, Prou D, Hananiya A, Markov D, Poulsen N, Larsen KE, Moore CM, Troyer MD, Edwards RH, Przedborski S, Sulzer D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 6;26(36):9304-11
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 6;26(36):9304-11
Lipid rafts mediate the synaptic localization of alpha-synuclein.
Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Jul 28;24(30):6715-23
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Jul 28;24(30):6715-23
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P
The Journal of biological chemistry 2001 Nov 16;276(46):42645-57
The Journal of biological chemistry 2001 Nov 16;276(46):42645-57
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
Kahle PJ, Neumann M, Ozmen L, Muller V, Jacobsen H, Schindzielorz A, Okochi M, Leimer U, van Der Putten H, Probst A, Kremmer E, Kretzschmar HA, Haass C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 Sep 1;20(17):6365-73
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 Sep 1;20(17):6365-73
Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies.
Neumann M, Adler S, Schlüter O, Kremmer E, Benecke R, Kretzschmar HA
Acta neuropathologica 2000 Nov;100(5):568-74
Acta neuropathologica 2000 Nov;100(5):568-74
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