AMM01161G

antibody from Leading Biology
Targeting: PAX7 Hup1
Provider product page for AMM01161G
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
AMM01161G - Provider product page
Provider
Leading Biology
Product name
PAX7 (Rhabdomyosarcoma Marker) Antibody
Antibody type
Monoclonal
Description
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
Reactivity
Human, Mouse, Rat, Chicken/Avian, Zebrafish
Host
Mouse
Antibody clone number
PAX7/497
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
PAX7 protein structure - AMM01161G shown in red.