PAB8503

antibody from Abnova Corporation

Targeting: TRPV4 CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB8503

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB8503, RRID:AB_1716534

Product name

Trpv4 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of Trpv4.

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Effects of body temperature on neural activity in the hippocampus: regulation of resting membrane potentials by transient receptor potential vanilloid 4.

Shibasaki K, Suzuki M, Mizuno A, Tominaga M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Feb 14;27(7):1566-75

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Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat.

Alessandri-Haber N, Dina OA, Yeh JJ, Parada CA, Reichling DB, Levine JD
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 May 5;24(18):4444-52

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Impaired osmotic sensation in mice lacking TRPV4.

Mizuno A, Matsumoto N, Imai M, Suzuki M
American journal of physiology. Cell physiology 2003 Jul;285(1):C96-101

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Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.

Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T, Nilius B
Nature 2003 Jul 24;424(6947):434-8

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Warm temperatures activate TRPV4 in mouse 308 keratinocytes.

Chung MK, Lee H, Caterina MJ
The Journal of biological chemistry 2003 Aug 22;278(34):32037-46

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of extract from Lane 1: choroid plexus (Wild type mouse) , Lane 2: choroid plexus (Trpv4 knockout mouse) and Lane 3: rat Trpv4 overexpressed in HEK 293T cells, using Trpv4 polyclonal antibody (Cat # PAB8503) .