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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunohistochemistry [1]
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- Product number
- AF2645 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal GFR alpha-3/GDNF R alpha-3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse GFR alpha-3/GDNF R alpha-3 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human GFR alpha-3 is observed and less than 2% cross-reactivity with recombinant mouse (rm) GFR alpha-2, rmGFR alpha-4, and recombinant rat GFR alpha-1 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Vascular-derived artemin: a determinant of vascular sympathetic innervation?
Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo.
Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold.
Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 21;114(12):E2486-E2493
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 21;114(12):E2486-E2493
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Albers KM, Zhang XL, Diges CM, Schwartz ES, Yang CI, Davis BM, Gold MS
Molecular pain 2014 May 22;10:31
Molecular pain 2014 May 22;10:31
Vascular-derived artemin: a determinant of vascular sympathetic innervation?
Damon DH, Teriele JA, Marko SB
American journal of physiology. Heart and circulatory physiology 2007 Jul;293(1):H266-73
American journal of physiology. Heart and circulatory physiology 2007 Jul;293(1):H266-73
Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo.
Malin SA, Molliver DC, Koerber HR, Cornuet P, Frye R, Albers KM, Davis BM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Aug 16;26(33):8588-99
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Aug 16;26(33):8588-99
Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold.
Elitt CM, McIlwrath SL, Lawson JJ, Malin SA, Molliver DC, Cornuet PK, Koerber HR, Davis BM, Albers KM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Aug 16;26(33):8578-87
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Aug 16;26(33):8578-87
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- GFRa‑3/GDNF Ra‑3 in Mouse Embryo. GFRa‑3/GDNF Ra‑3 in Mouse Embryo.
