BS7947

antibody from Bioworld Technology, Inc
Targeting: KDM3B C5orf7, JMJD1B, KIAA1082, NET22
Provider product page for BS7947
Western blot
Immunohistochemistry

Antibody data

Product number
BS7947 - Provider product page
Provider
Bioworld Technology, Inc
Product name
KDM3B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human KDM3B-KDM3A.
Description
JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KDM3B protein structure - BS7947 shown in red.