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Western blot
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- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500030 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- Integrin alpha 4 antibody was raised against a 16 amino acid peptide from near the center of human Integrin alpha 4. (AP30435CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).
Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.
Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopes.
Wegener KL, Campbell ID
Molecular membrane biology 2008 Aug;25(5):376-87
Molecular membrane biology 2008 Aug;25(5):376-87
Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)
Kamata T, Puzon W, Takada Y
The Biochemical journal 1995 Feb 1;305 ( Pt 3):945-51
The Biochemical journal 1995 Feb 1;305 ( Pt 3):945-51
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.
Berlin C, Berg EL, Briskin MJ, Andrew DP, Kilshaw PJ, Holzmann B, Weissman IL, Hamann A, Butcher EC
Cell 1993 Jul 16;74(1):185-95
Cell 1993 Jul 16;74(1):185-95
Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopes.
Pulido R, Elices MJ, Campanero MR, Osborn L, Schiffer S, García-Pardo A, Lobb R, Hemler ME, Sánchez-Madrid F
The Journal of biological chemistry 1991 Jun 5;266(16):10241-5
The Journal of biological chemistry 1991 Jun 5;266(16):10241-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Integrin alpha 4 using (A) 25 and (B) 100 ng of recombinant Integrin alpha 4 with AP30435PU-N Integrin alpha 4 antibody at 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of Integrin alpha 4 in Jurkat cells with AP30435PU-N Integrin alpha 4 antibody at 2 ?g/ml.
