BS8149

antibody from Bioworld Technology, Inc
Targeting: PDLIM3 ALP
Provider product page for BS8149
Western blot
Immunohistochemistry

Antibody data

Product number
BS8149 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PDLIM3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PDLIM3.
Description
ALP (actinin-associated LIM protein), also known as PDLIM3 (PDZ and LIM domain protein 3) is a 364 amino acid protein that contains one LIM zinc-binding domain and one PDZ domain and localizes to the cytoplasm, as well as to myofiber Z-lines. Existing as three alternatively spliced isoforms, two of which exhibit tissue-specific expression in skeletal muscle and heart, ALP interacts with Ï«-actinin-2 and, via this interaction, is thought to play a role in Actin filament organization, specifically regulating the association of Actin filaments arrays with muscle cells. The gene encoding ALP maps to a region on human chromosome 4 that is associated with facioscapulohumeral muscular dystrophy, suggesting that defects in the ALP gene may be involved in the pathogenesis of muscular dystrophy.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PDLIM3 protein structure - BS8149 shown in red.