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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB10265 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB10265, RRID:AB_1671705
- Product name
- CRTC1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CRTC1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes.
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway.
TORCs: transducers of regulated CREB activity.
Coxon A, Rozenblum E, Park YS, Joshi N, Tsurutani J, Dennis PA, Kirsch IR, Kaye FJ
Cancer research 2005 Aug 15;65(16):7137-44
Cancer research 2005 Aug 15;65(16):7137-44
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway.
Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ
Nature genetics 2003 Feb;33(2):208-13
Nature genetics 2003 Feb;33(2):208-13
TORCs: transducers of regulated CREB activity.
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M
Molecular cell 2003 Aug;12(2):413-23
Molecular cell 2003 Aug;12(2):413-23
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot using CRTC1 polyclonal antibody (Cat # PAB10265) shows detection of CRTC1 (lower arrowhead) and CRTC1 : MAML2 fusion protein (top arrowhead) in cell lysates.Lane 1 contains lysate from cells expressing CRTC1 only.Lane 2 contains lysate from cells transfected with fusion protein.Lane 3 contains lysate from cells strongly expressing CRTC1 and weakly expressing the fusion protein.Lane 4 contains lysate from control cells. After SDS-PAGE and transfer, the membrane was probed with the primary antibody diluted to 1:1,000.Personal Communication, Frederick Kaye, CCR-NCI, Bethesda, MD.
