UPF1

gene product
HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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204 antibodies from 26 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Atlas Antibodies
2 antibodies
Bethyl Laboratories, Inc.
10 antibodies
Novus Biologicals
9 antibodies
OriGene
4 antibodies
NovoPro Bioscience Inc.
1 antibody
Abnova Corporation
3 antibodies
antibodies-online
56 antibodies
Proteintech Group
1 antibody
Bioworld Technology, Inc
1 antibody
GeneTex
5 antibodies
Aviva Systems Biology
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Invitrogen Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
19 antibodies
RabMAbs
4 antibodies
Acris Antibodies GmbH
4 antibodies
Biorbyt
10 antibodies
Abgent
1 antibody
R&D Systems
1 antibody
United States Biological
38 antibodies
St John's Laboratory
2 antibodies
MyBioSource
3 antibodies
EMD Millipore
5 antibodies
Sigma-Aldrich
3 antibodies
GenWay
3 antibodies