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- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 13560-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13560-1-AP, RRID:AB_2067220
- Product name
- BST2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BST2 antibody (Cat. #13560-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
BST2 suppresses LINE-1 retrotransposition by reducing the promoter activity of LINE-1 5'-UTR.
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction.
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion.
Differential interferon pathway gene expression patterns in Rhabdomyosarcoma cells during Enterovirus 71 or Coxsackievirus A16 infection.
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.
BST2/Tetherin inhibits hepatitis C virus production in human hepatoma cells.
BST2/tetherin inhibits dengue virus release from human hepatoma cells.
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Gao W, Rui Y, Li G, Zhai C, Su J, Liu H, Zheng W, Zheng B, Zhang W, Yang Y, Hua S, Yu X
Frontiers in immunology 2021;12:740713
Frontiers in immunology 2021;12:740713
BST2 suppresses LINE-1 retrotransposition by reducing the promoter activity of LINE-1 5'-UTR.
Zhao Y, Du J, Wang Y, Wang Q, Wang S, Zhao K
Journal of virology 2021 Nov 3;:JVI0161021
Journal of virology 2021 Nov 3;:JVI0161021
The viral restriction factor tetherin/BST2 tethers cytokinetic midbody remnants to the cell surface.
Presle A, Frémont S, Salles A, Commere PH, Sassoon N, Berlioz-Torrent C, Gupta-Rossi N, Echard A
Current biology : CB 2021 May 24;31(10):2203-2213.e5
Current biology : CB 2021 May 24;31(10):2203-2213.e5
ATP1B3 cooperates with BST-2 to promote hepatitis B virus restriction.
Zheng B, Zhang J, Zheng T, Wang H, Li Z, Huan C, Ning S, Wang Y, Zhang W
Journal of medical virology 2020 Feb;92(2):201-209
Journal of medical virology 2020 Feb;92(2):201-209
MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer.
Liu W, Li Y, Feng S, Guan Y, Cao Y
Journal of biochemistry 2020 Aug 1;168(2):159-170
Journal of biochemistry 2020 Aug 1;168(2):159-170
Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2.
Heusinger E, Deppe K, Sette P, Krapp C, Kmiec D, Kluge SF, Marx PA, Apetrei C, Kirchhoff F, Sauter D
Journal of virology 2018 Sep 15;92(18)
Journal of virology 2018 Sep 15;92(18)
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Liu W, Cao Y, Guan Y, Zheng C
Biotechnology letters 2018 Jul;40(7):1015-1027
Biotechnology letters 2018 Jul;40(7):1015-1027
Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection.
Fu Y, Zhang L, Zhang F, Tang T, Zhou Q, Feng C, Jin Y, Wu Z
PLoS pathogens 2017 Sep;13(9):e1006611
PLoS pathogens 2017 Sep;13(9):e1006611
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Jin S, Tian S, Luo M, Xie W, Liu T, Duan T, Wu Y, Cui J
Molecular cell 2017 Oct 19;68(2):308-322.e4
Molecular cell 2017 Oct 19;68(2):308-322.e4
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion.
Yan R, Zhao X, Cai D, Liu Y, Block TM, Guo JT, Guo H
Journal of virology 2015 Sep;89(18):9200-12
Journal of virology 2015 Sep;89(18):9200-12
Differential interferon pathway gene expression patterns in Rhabdomyosarcoma cells during Enterovirus 71 or Coxsackievirus A16 infection.
Zhang W, Zhang L, Wu Z, Tien P
Biochemical and biophysical research communications 2014 May 9;447(3):550-5
Biochemical and biophysical research communications 2014 May 9;447(3):550-5
Interferon induction of IFITM proteins promotes infection by human coronavirus OC43.
Zhao X, Guo F, Liu F, Cuconati A, Chang J, Block TM, Guo JT
Proceedings of the National Academy of Sciences of the United States of America 2014 May 6;111(18):6756-61
Proceedings of the National Academy of Sciences of the United States of America 2014 May 6;111(18):6756-61
BST2/Tetherin inhibits hepatitis C virus production in human hepatoma cells.
Pan XB, Qu XW, Jiang D, Zhao XL, Han JC, Wei L
Antiviral research 2013 Apr;98(1):54-60
Antiviral research 2013 Apr;98(1):54-60
BST2/tetherin inhibits dengue virus release from human hepatoma cells.
Pan XB, Han JC, Cong X, Wei L
PloS one 2012;7(12):e51033
PloS one 2012;7(12):e51033
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Weidner JM, Jiang D, Pan XB, Chang J, Block TM, Guo JT
Journal of virology 2010 Dec;84(24):12646-57
Journal of virology 2010 Dec;84(24):12646-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 13560-1-AP(BST2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 13560-1-AP(BST2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 13560-1-AP(BST2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BST2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BST2. This antibody recognizes human antigen. The BST2 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
