66666-1-Ig

antibody from Proteintech Group

Targeting: PROM1 AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4

Provider product page for 66666-1-Ig

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Immunohistochemistry

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Antibody data

Antibody Data
Antigen structure
References [24]
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Product number: 66666-1-Ig - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#66666-1-Ig, RRID:AB_2801586
Product name: CD133 antibody
Antibody type: Monoclonal
Description: CD133 antibody (Cat. #66666-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: FC, IHC, WB,ELISA.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 2B8A2
Vial size: 20ul, 150ul

PROM1 protein structure - 66666-1-Ig shown in red.

Submitted references ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.

Cui Y, Yang J, Bai Y, Li Q, Yao Y, Liu C, Wu F, Zhang J, Zhang Y
Frontiers in cell and developmental biology 2021;9:616887

The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.

Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y, Li L
Frontiers in oncology 2021;11:637298

Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.

Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, Jiang M, Lin W, Zhang Y, Lin W, Zhou R, Zhao L
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297

Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.

Nong S, Wei Z, Wang Z, Ma L, Guan Y, Ni J
Stem cells and development 2021 Sep 15;30(18):934-945

Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.

Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849

The critical role of peroxiredoxin-2 in colon cancer stem cells.

Peng L, Xiong Y, Wang R, Xiang L, Zhou H, Fu Z
Aging 2021 Mar 26;13(8):11170-11187

EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis.

Wang K, Wang Y, Wang Y, Liu S, Wang C, Zhang S, Zhang T, Yang X
Stem cell research & therapy 2021 Mar 16;12(1):186

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.

Wang C, Jing J, Hu X, Yu S, Yao F, Li Z, Cheng L
Journal of cellular and molecular medicine 2021 Jun 5;

Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.

Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615

The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.

Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373

Parthenolide inhibits the tumor characteristics of renal cell carcinoma.

Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110

Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.

Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150

Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.

Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146

Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis.

Yan J, Wang WB, Fan YJ, Bao H, Li N, Yao QP, Huo YL, Jiang ZL, Qi YX, Han Y
Frontiers in cell and developmental biology 2020;8:606989

MiR-153 reduces stem cell-like phenotype and tumor growth of lung adenocarcinoma by targeting Jagged1.

Zhao G, Zhang Y, Zhao Z, Cai H, Zhao X, Yang T, Chen W, Yao C, Wang Z, Wang Z, Han C, Wang H
Stem cell research & therapy 2020 May 6;11(1):170

Ginsenoside Rg3 attenuates the osimertinib resistance by reducing the stemness of non-small cell lung cancer cells.

Tan Q, Lin S, Zeng Y, Yao M, Liu K, Yuan H, Liu C, Jiang G
Environmental toxicology 2020 Jun;35(6):643-651

Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.

Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196

Comprehensive profiling identifies a novel signature with robust predictive value and reveals the potential drug resistance mechanism in glioma.

Zeng F, Wang K, Liu X, Zhao Z
Cell communication and signaling : CCS 2020 Jan 6;18(1):2

RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA.

Wu X, Wang Y, Zhong W, Cheng H, Tian Z
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 23;26:e921389

lncRNA TPTEP1 inhibits stemness and radioresistance of glioma through miR‑106a‑5p‑mediated P38 MAPK signaling.

Tang T, Wang LX, Yang ML, Zhang RM
Molecular medicine reports 2020 Dec;22(6):4857-4867

ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.

Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312

Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells.

Zhao H, Yan C, Hu Y, Mu L, Huang K, Li Q, Li X, Tao D, Qin J
International journal of oncology 2019 Mar;54(3):893-904

Gab2 Ablation Reverses the Stemness of HER2-Overexpressing Breast Cancer Cells.

Zhang P, Chen Y, Gong M, Zhuang Z, Wang Y, Mu L, Wang T, Pan J, Liu Y, Xu J, Liang R, Yuan Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(1):52-65

Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma.

Yang LH, Wang Y, Qiao S, Wang MJ, Chen F, Zi XY, Li JX, Zhang HB, Yu B, Hu YP
Cancer management and research 2018;10:873-885

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