KCNK5

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]

Description

Potassium two pore domain channel subfamily K member 5

Tissue specificity

Tissue enhanced (intestine, kidney)

Subcell location

Nucleoplasm

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters
Voltage-gated ion channels

Chromosome

6 (39188971 - 39229475)

Ensembl ID

ENSG00000164626  (ver. 103.38)

Orthologs

Mouse Kcnk5: ENSMUSG00000023243

UniProt

O95279

neXtProt

NX_O95279

Human splice variants
Mouse splice variants

Protein structure