13372-1-AP

antibody from Proteintech Group

Targeting: TFEB bHLHe35, TCFEB

Provider product page for 13372-1-AP

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ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [74]
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Validations
Western blot [1]
Immunocytochemistry [1]
Immunoprecipitation [1]
Immunohistochemistry [2]

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Product number: 13372-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13372-1-AP, RRID:AB_2199611
Product name: TFEB antibody
Antibody type: Polyclonal
Description: KD/KO validated TFEB antibody (Cat. #13372-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

TFEB protein structure - 13372-1-AP shown in red.

Submitted references Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.

Deng L, Liu W, Xu Q, Guo R, Zhang D, Ni J, Li L, Cai X, Fan G, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112383

Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.

Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310

Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy.

Shyam R, Ogando DG, Choi M, Liton PB, Bonanno JA
Investigative ophthalmology & visual science 2021 Sep 2;62(12):15

Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons.

Wu Z, Zhang Y, Liu Y, Chen X, Huang Z, Zhao X, He H, Deng Y
Life (Basel, Switzerland) 2021 Sep 10;11(9)

TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading.

Xu Y, Du S, Marsh JA, Horie K, Sato C, Ballabio A, Karch CM, Holtzman DM, Zheng H
Molecular psychiatry 2021 Oct;26(10):5925-5939

Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair.

Wang B, Cao C, Han D, Bai J, Guo J, Guo Q, Li D, Zhang J, Zhang Z, Wang Y, Tang J, Shen D, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112056

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.

Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031

TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.

Suzuki N, Johmura Y, Wang TW, Migita T, Wu W, Noguchi R, Yamaguchi K, Furukawa Y, Nakamura S, Miyoshi I, Yoshimori T, Ohta T, Nakanishi M
Autophagy 2021 Nov;17(11):3776-3793

Positive regulation of TFEB and mitophagy by PGC-1α to alleviate LPS-induced acute lung injury in rats.

Liu W, Li Y, Bo L, Li C, Jin F
Biochemical and biophysical research communications 2021 Nov 5;577:1-5

SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.

Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2021 Nov 29;

Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.

Li D, Cui Y, Wang X, Liu F, Li X
Phytotherapy research : PTR 2021 Mar;35(3):1416-1431

20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes.

Gu M, Jin J, Ren C, Chen X, Pan Z, Wu Y, Tian N, Sun L, Wu A, Gao W, Zhou Y, Lin Z, Zhang X
Pharmacological research 2021 Mar;165:105361

Transcription factor EB (TFEB)-mediated autophagy protects bovine mammary epithelial cells against H₂O₂-induced oxidative damage in vitro.

Sun X, Chang R, Tang Y, Luo S, Jiang C, Jia H, Xu Q, Dong Z, Liang Y, Loor JJ, Xu C
Journal of animal science and biotechnology 2021 Mar 9;12(1):35

YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.

Ikeda S, Nah J, Shirakabe A, Zhai P, Oka SI, Sciarretta S, Guan KL, Shimokawa H, Sadoshima J
The Journal of clinical investigation 2021 Mar 1;131(5)

Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.

Zhang X, Wei M, Fan J, Yan W, Zha X, Song H, Wan R, Yin Y, Wang W
Autophagy 2021 Jun;17(6):1519-1542

Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer.

Liu W, Wang Y, Xie Y, Dai T, Fan M, Li C, Zou Y
Cell death discovery 2021 Jun 5;7(1):136

Lysosomal nitric oxide determines transition from autophagy to ferroptosis after exposure to plasma-activated Ringer's lactate.

Jiang L, Zheng H, Lyu Q, Hayashi S, Sato K, Sekido Y, Nakamura K, Tanaka H, Ishikawa K, Kajiyama H, Mizuno M, Hori M, Toyokuni S
Redox biology 2021 Jul;43:101989

By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.

Che Y, Wang Z, Yuan Y, Zhou H, Wu H, Wang S, Tang Q
Cell biology and toxicology 2021 Jul 22;

Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway.

Fang S, Wan X, Zou X, Sun S, Hao X, Liang C, Zhang Z, Zhang F, Sun B, Li H, Yu B
Cell death & disease 2021 Jan 18;12(1):88

Quercetin alleviates Cadmium-induced autophagy inhibition via TFEB-dependent lysosomal restoration in primary proximal tubular cells.

Zhao Y, Li ZF, Zhang D, Wang ZY, Wang L
Ecotoxicology and environmental safety 2021 Jan 15;208:111743

PMEPA1 and NEDD4 control the proton production of osteoclasts by regulating vesicular trafficking.

Hirata H, Xu X, Nishioka K, Matsuhisa F, Kitajima S, Kukita T, Murayama M, Urano Y, Miyamoto H, Mawatari M, Kukita A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21281

Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells.

Wang S, Guo R, Su Y, Yang C, Guo Y, Tan C, Zhao B
Chemico-biological interactions 2021 Feb 25;336:109319

Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.

Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515

Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.

Zhang H, Lu J, Liu H, Guan L, Xu S, Wang Z, Qiu Y, Liu H, Peng L, Men X
Pharmacological research 2021 Dec;174:105964

A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.

Kataura T, Tashiro E, Nishikawa S, Shibahara K, Muraoka Y, Miura M, Sakai S, Katoh N, Totsuka M, Onodera M, Shin-Ya K, Miyamoto K, Sasazawa Y, Hattori N, Saiki S, Imoto M
Autophagy 2021 Aug;17(8):1856-1872

TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells.

Relic B, Deroyer C, Malaise O, Plener Z, Gillet P, de Seny D, Malaise MG
The Biochemical journal 2021 Aug 27;478(16):3145-3155

TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.

Yang CB, Liu J, Tong BC, Wang ZY, Zhu Z, Su CF, Sreenivasmurthy SG, Wu JX, Iyaswamy A, Krishnamoorthi S, Huang SY, Cheung KH, Song JX, Tan JQ, Lu JH, Li M
Acta pharmacologica Sinica 2021 Aug 20;

Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.

Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250

Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.

Zhang S, Zhang Y, Zhang X, Luo C, Cao Y, Ji D, Yan W, Xue K, Chai J, Dai H, Wang W
Oxidative medicine and cellular longevity 2020;2020:4252047

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.

Xu Q, Fan Y, Loor JJ, Liang Y, Sun X, Jia H, Zhao C, Xu C
Frontiers in pharmacology 2020;11:601716

3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages.

Liu N, Yang Y, Chen J, Jia H, Zhang Y, Jiang D, Wu G, Wu Z
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt B):114697

HGF protected against diabetic nephropathy via autophagy-lysosome pathway in podocyte by modulating PI3K/Akt-GSK3β-TFEB axis.

Hou B, Li Y, Li X, Zhang C, Zhao Z, Chen Q, Zhang N, Li H
Cellular signalling 2020 Nov;75:109744

Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.

Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659

PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.

Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991

Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells.

Otsu W, Ishida K, Nakamura S, Shimazawa M, Tsusaki H, Hara H
Biochemical and biophysical research communications 2020 May 28;526(2):479-484

TFEB-NF-κB inflammatory signaling axis: a novel therapeutic pathway of Dihydrotanshinone I in doxorubicin-induced cardiotoxicity.

Wang X, Wang Q, Li W, Zhang Q, Jiang Y, Guo D, Sun X, Lu W, Li C, Wang Y
Journal of experimental & clinical cancer research : CR 2020 May 24;39(1):93

Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease.

Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, Wen Y, Zou F, Li W
Aging cell 2020 Jun;19(6):e13163

The Establishment and Application Studies on Precise Lysosome pH Indicator Based on Self-Decomposable Nanoparticles.

Pang C, Song C, Li Y, Wang Q, Zhu X, Wu J, Tian Y, Fan H, Hu J, Li C, Wang B, Li X, Liu W, Fan L
Nanoscale research letters 2020 Jul 8;15(1):143

Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.

He X, Chen S, Li C, Ban J, Wei Y, He Y, Liu F, Chen Y, Chen J
Cells 2020 Jan 4;9(1)

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.

Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L
Nature communications 2020 Jan 24;11(1):479

A Self-Assembled α-Synuclein Nanoscavenger for Parkinson's Disease.

Liu J, Liu C, Zhang J, Zhang Y, Liu K, Song JX, Sreenivasmurthy SG, Wang Z, Shi Y, Chu C, Zhang Y, Wu C, Deng X, Liu X, Song J, Zhuang R, Huang S, Zhang P, Li M, Wen L, Zhang YW, Liu G
ACS nano 2020 Feb 25;14(2):1533-1549

LSD1 negatively regulates autophagy in myoblast cells by driving PTEN degradation.

Shi YX, He YJ, Zhou Y, Li HK, Yang D, Li RY, Deng ZL, Gao YF
Biochemical and biophysical research communications 2020 Feb 19;522(4):924-930

The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper-zinc superoxide dismutase 1-mediated toxicity.

Ito T, Inden M, Ueda T, Asaka Y, Kurita H, Hozumi I
Scientific reports 2020 Dec 17;10(1):22157

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS.

Cunningham KM, Maulding K, Ruan K, Senturk M, Grima JC, Sung H, Zuo Z, Song H, Gao J, Dubey S, Rothstein JD, Zhang K, Bellen HJ, Lloyd TE
eLife 2020 Dec 10;9

Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy.

Li B, Wu J, Bao J, Han X, Shen S, Ye X, Dai J, Wu Z, Niu M, He Y, Ni J, Wen L, Wang X, Hu G
Biochimica et biophysica acta. Molecular basis of disease 2020 Dec 1;1866(12):165971

Remote ischemic postconditioning attenuates damage in rats with chronic cerebral ischemia by upregulating the autophagolysosome pathway via the activation of TFEB.

Li Z, Cui X, Lv H, Liu J, Di W, Jiang F, Liu Y, Cheng X
Experimental and molecular pathology 2020 Aug;115:104475

NAD⁺ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux.

Zhang YJ, Zhang M, Zhao X, Shi K, Ye M, Tian J, Guan S, Ying W, Qu X
Basic research in cardiology 2020 Aug 10;115(5):57

Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.

Unno R, Kawabata T, Taguchi K, Sugino T, Hamamoto S, Ando R, Okada A, Kohri K, Yoshimori T, Yasui T
Autophagy 2020 Apr;16(4):709-723

Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.

Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005

Loss of spatacsin impairs cholesterol trafficking and calcium homeostasis.

Boutry M, Pierga A, Matusiak R, Branchu J, Houllegatte M, Ibrahim Y, Balse E, El Hachimi KH, Brice A, Stevanin G, Darios F
Communications biology 2019;2:380

Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.

Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, Sun T
Nutrition & metabolism 2019;16:87

TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation.

Cheng D, Tan Q, Zhu Q, Zhang J, Han X, Fang P, Jin W, Liu X
Frontiers in human neuroscience 2019;13:108

Irisin reverses insulin resistance in C2C12 cells via the p38-MAPK-PGC-1α pathway.

Ye X, Shen Y, Ni C, Ye J, Xin Y, Zhang W, Ren Y
Peptides 2019 Sep;119:170120

TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.

Yamamoto F, Taniguchi K, Mamada N, Tamaoka A, Kametani F, Lakshmana MK, Araki W
Neuroscience 2019 Mar 15;402:11-22

Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress.

Chakraborty D, Felzen V, Hiebel C, Stürner E, Perumal N, Manicam C, Sehn E, Grus F, Wolfrum U, Behl C
Redox biology 2019 Jun;24:101181

NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer.

Song X, Liu L, Chang M, Geng X, Wang X, Wang W, Chen TC, Xie L, Song X
Journal of experimental & clinical cancer research : CR 2019 Jun 7;38(1):239

Overexpression of transcription factor EB regulates mitochondrial autophagy to protect lipopolysaccharide-induced acute lung injury.

Liu W, Li CC, Lu X, Bo LY, Jin FG
Chinese medical journal 2019 Jun 5;132(11):1298-1304

Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1.

Wang X, Li C, Wang Q, Li W, Guo D, Zhang X, Shao M, Chen X, Ma L, Zhang Q, Wang W, Wang Y
Cancers 2019 Jun 28;11(7)

mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation.

Abe K, Yano T, Tanno M, Miki T, Kuno A, Sato T, Kouzu H, Nakata K, Ohwada W, Kimura Y, Sugawara H, Shibata S, Igaki Y, Ino S, Miura T
Biochimica et biophysica acta. Molecular basis of disease 2019 Dec 1;1865(12):165552

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.

Kang Y, Li Y, Zhang T, Chi Y, Liu M
International journal of molecular medicine 2019 Aug;44(2):447-456

TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.

He R, Wang M, Zhao C, Shen M, Yu Y, He L, Zhao Y, Chen H, Shi X, Zhou M, Pan S, Liu Y, Guo X, Li X, Qin R
Journal of experimental & clinical cancer research : CR 2019 Aug 6;38(1):340

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.

Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Journal of lipid research 2019 Apr;60(4):844-855

Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.

Lotfi P, Tse DY, Di Ronza A, Seymour ML, Martano G, Cooper JD, Pereira FA, Passafaro M, Wu SM, Sardiello M
Autophagy 2018;14(8):1419-1434

A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration.

Jin MM, Wang F, Qi D, Liu WW, Gu C, Mao CJ, Yang YP, Zhao Z, Hu LF, Liu CF
Frontiers in aging neuroscience 2018;10:378

Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.

Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243

Autophagic Modulation by Trehalose Reduces Accumulation of TDP-43 in a Cell Model of Amyotrophic Lateral Sclerosis via TFEB Activation.

Wang Y, Liu FT, Wang YX, Guan RY, Chen C, Li DK, Bu LL, Song J, Yang YJ, Dong Y, Chen Y, Wang J
Neurotoxicity research 2018 Jul;34(1):109-120

TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation.

Zheng G, Zhan Y, Li X, Pan Z, Zheng F, Zhang Z, Zhou Y, Wu Y, Wang X, Gao W, Xu H, Tian N, Zhang X
Cell death & disease 2018 Aug 28;9(9):858

Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome.

Yang Y, Qin M, Bao P, Xu W, Xu J
PloS one 2017;12(7):e0180892

Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.

Shi L, Ito F, Wang Y, Okazaki Y, Tanaka H, Mizuno M, Hori M, Hirayama T, Nagasawa H, Richardson DR, Toyokuni S
Free radical biology & medicine 2017 Jul;108:904-917

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.

Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M
Nature communications 2017 Feb 6;8:14338

Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.

Kobayashi T, Tsutsui H, Shimabukuro-Demoto S, Yoshida-Sugitani R, Karyu H, Furuyama-Tanaka K, Ohshima D, Kato N, Okamura T, Toyama-Sorimachi N
International immunology 2017 Dec 31;29(12):551-566

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.

Ahuja S, Knudsen L, Chillappagari S, Henneke I, Ruppert C, Korfei M, Gochuico BR, Bellusci S, Seeger W, Ochs M, Guenther A, Mahavadi P
American journal of physiology. Lung cellular and molecular physiology 2016 Mar 15;310(6):L519-31

Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.

Wang HS, Pei F, Chen Z, Zhang L
Journal of dental research 2016 Jun;95(6):697-703

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.

Song JX, Sun YR, Peluso I, Zeng Y, Yu X, Lu JH, Xu Z, Wang MZ, Liu LF, Huang YY, Chen LL, Durairajan SS, Zhang HJ, Zhou B, Zhang HQ, Lu A, Ballabio A, Medina DL, Guo Z, Li M
Autophagy 2016 Aug 2;12(8):1372-89

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Jurkat cells were subjected to SDS PAGE followed by western blot with 13372-1-AP(TFEB antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of Hela cells, using TFEB antibody 13372-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: IP Result of anti-TFEB (IP:13372-1-AP, 3ug; Detection:13372-1-AP 1:1000) with NIH/3T3 cells lysate 3300ug.
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human renal cell carcinoma using 13372-1-AP(TFEB antibody) at dilution of 1:50 (under 10x lens)
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human renal cell carcinoma using 13372-1-AP(TFEB antibody) at dilution of 1:50 (under 40x lens)
Sample type: cell line