Tissue expression
Cell line expression
Protein structure
ADRB2
Adrenoceptor beta 2ADRB2R, ADRBR, B2AR, BAR
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
Top validated antibodies |
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Proteintech Group | 13096-1-AP | 14 references | Polyclonal |
WB
EL
IHC
FC |
|
antibodies-online | ABIN5862415 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Enzo Life Sciences | ADI-905-742-100 | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | PA5-38403 | 2 references | Polyclonal |
WB
IHC
OA
|
|
Novus Biologicals | H00000154-B01P | 2 references | Polyclonal |
WB
ICC
FC
|
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