Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
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Validation data
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- Product number
- GTX85173 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX85173, RRID:AB_10724347
- Product name
- SCUBE2 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Rat
- Host
- Rabbit
Submitted references Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition.
Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis.
Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.
Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition.
Chen JH, Kuo KT, Bamodu OA, Lin YC, Yang RB, Yeh CT, Chao TY
Experimental cell research 2018 Sep 15;370(2):444-453
Experimental cell research 2018 Sep 15;370(2):444-453
Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis.
Lin YC, Liu CY, Kannagi R, Yang RB
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1202-1215
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1202-1215
Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.
Lin YC, Chao TY, Yeh CT, Roffler SR, Kannagi R, Yang RB
Arteriosclerosis, thrombosis, and vascular biology 2017 Jan;37(1):144-155
Arteriosclerosis, thrombosis, and vascular biology 2017 Jan;37(1):144-155
Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition.
Lin YC, Lee YC, Li LH, Cheng CJ, Yang RB
Journal of cell science 2014 Jan 1;127(Pt 1):85-100
Journal of cell science 2014 Jan 1;127(Pt 1):85-100
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western blot analysis of SCUBE2 in Daudi cell lysate with SCUBE2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
- Validation comment
- WB
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunocytochemistry of SCUBE2 in Daudi cells with SCUBE2 antibody at 20 μg/ml.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence of SCUBE2 in Daudi cells with SCUBE2 antibody at 20 μg/mL.