Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 12781-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12781-1-AP, RRID:AB_2275326
- Product name
- CBLB antibody
- Antibody type
- Polyclonal
- Description
- CBLB antibody (Cat. #12781-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cbl-b deficiency prevents functional but not phenotypic T cell anergy.
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway.
Ubiquitination and functional modification of GluN2B subunit-containing NMDA receptors by Cbl-b in the spinal cord dorsal horn.
NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection.
A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function.
Nguyen TTT, Wang ZE, Shen L, Schroeder A, Eckalbar W, Weiss A
The Journal of experimental medicine 2021 Jul 5;218(7)
The Journal of experimental medicine 2021 Jul 5;218(7)
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Han S, Li X, Liu J, Zou Z, Luo L, Wu R, Zhao Z, Wang C, Shen B
Frontiers in veterinary science 2020;7:529
Frontiers in veterinary science 2020;7:529
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Chen K, Wan X, Zhao L, Zhao S, Peng L, Yang W, Yuan J, Zhu L, Mo Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway.
BommaReddy RR, Patel R, Smalley T, Acevedo-Duncan M
OncoTargets and therapy 2020;13:1661-1676
OncoTargets and therapy 2020;13:1661-1676
Ubiquitination and functional modification of GluN2B subunit-containing NMDA receptors by Cbl-b in the spinal cord dorsal horn.
Zhang ZY, Bai HH, Guo Z, Li HL, Diao XT, Zhang TY, Yao L, Ma JJ, Cao Z, Li YX, Bai X, Chen HK, Suo ZW, Yang X, Hu XD
Science signaling 2020 Jun 30;13(638)
Science signaling 2020 Jun 30;13(638)
NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection.
Pu ZQ, Liu D, Lobo Mouguegue HPP, Jin CW, Sadiq E, Qin DD, Yu TF, Zong C, Chen JC, Zhao RX, Lin JY, Cheng J, Yu X, Li X, Zhang YC, Liu YT, Guan QB, Wang XD
Journal of cellular and molecular medicine 2020 Dec;24(24):14171-14183
Journal of cellular and molecular medicine 2020 Dec;24(24):14171-14183
A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function.
Stürner KH, Borgmeyer U, Schulze C, Pless O, Martin R
Journal of immunology (Baltimore, Md. : 1950) 2014 Nov 1;193(9):4439-47
Journal of immunology (Baltimore, Md. : 1950) 2014 Nov 1;193(9):4439-47
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 12781-1-AP(CBLB antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CBLB antibody 12781-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 12781-1-AP(CBLB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue