316006

antibody from BioLegend
Targeting: CD52 CDW52, EDDM5, HE5
Provider product page for 316006

Antibody data

Product number
316006 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#316006, RRID:AB_830791
Product name
PE anti-human CD52
Antibody type
Monoclonal
Antigen
Human tonsil
Description
CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. The HI186 antibody is useful for flow cytometry and immunohistochemistry.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CD52 protein structure - 316006 shown in red.