BS8143

antibody from Bioworld Technology, Inc
Targeting: JADE1 JADE-1, PHF17
Provider product page for BS8143
Western blot
Immunohistochemistry

Antibody data

Product number
BS8143 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PHF17 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PHF17.
Description
Jade-1, also known as PHF17 (PHD finger protein 17), is an 842 amino acid protein that localizes to both the cytoplasm and the nucleus and contains two PHD-type zinc fingers. Expressed at high levels in kidney tissue and also present in heart, pancreas and liver, Jade-1 functions as a transcriptional coactivator that, via its PHD zinc fingers, promotes the TIP30-dependent acetylation of Histone H4. Additionally, Jade-1 is thought to promote apoptosis and is down-regulated in renal carcinoma cells, suggesting a possible role in tumor suppression. Three isoforms of Jade-1, two of which are designated JADE1L and JADE1S, are produced via alternative splicing events. The gene encoding Jade-1 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
JADE1 protein structure - BS8143 shown in red.