Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14979-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14979-1-AP, RRID:AB_2136768
- Product name
- Galectin-3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Galectin-3 antibody (Cat. #14979-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Assessment of mitochondrial function in metabolic dysfunction-associated fatty liver disease using obese mouse models.
Activation of Galectin-3 (LGALS3) Transcription by Injurious Stimuli in the Liver Is Commonly Mediated by BRG1.
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.
Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling.
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
Cell cycle arrest in a model of colistin nephrotoxicity.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2021 Nov 24;
Inflammation 2021 Nov 24;
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Xiao M, Zhang M, Bie M, Wang X, Guo J, Xiao H
Cardiology 2020;145(7):446-455
Cardiology 2020;145(7):446-455
Assessment of mitochondrial function in metabolic dysfunction-associated fatty liver disease using obese mouse models.
Zhao QY, Ge LH, Zhang K, Chen HF, Zhan XX, Yang Y, Dang QL, Zheng Y, Zhou HB, Lyu JX, Fang HZ
Zoological research 2020 Sep 18;41(5):539-551
Zoological research 2020 Sep 18;41(5):539-551
Activation of Galectin-3 (LGALS3) Transcription by Injurious Stimuli in the Liver Is Commonly Mediated by BRG1.
Li Z, Lv F, Dai C, Wang Q, Jiang C, Fang M, Xu Y
Frontiers in cell and developmental biology 2019;7:310
Frontiers in cell and developmental biology 2019;7:310
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Nakamura H, Shimizu T, Takatani A, Suematsu T, Nakamura T, Kawakami A
Virus research 2019 Aug;269:197643
Virus research 2019 Aug;269:197643
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.
Li T, Zha L, Luo H, Li S, Zhao L, He J, Li X, Qi Q, Liu Y, Yu Z
Aging and disease 2019 Aug;10(4):731-745
Aging and disease 2019 Aug;10(4):731-745
Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling.
Xu WW, Zheng CC, Huang YN, Chen WY, Yang QS, Ren JY, Wang YM, He QY, Liao HX, Li B
Journal of agricultural and food chemistry 2018 Sep 5;66(35):9248-9258
Journal of agricultural and food chemistry 2018 Sep 5;66(35):9248-9258
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Luo H, Liu B, Zhao L, He J, Li T, Zha L, Li X, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
He J, Li X, Luo H, Li T, Zhao L, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S
Nature immunology 2016 Dec;17(12):1361-1372
Nature immunology 2016 Dec;17(12):1361-1372
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
Zhang RN, Zheng B, Li LM, Zhang J, Zhang XH, Wen JK
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H552-62
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H552-62
Cell cycle arrest in a model of colistin nephrotoxicity.
Eadon MT, Hack BK, Alexander JJ, Xu C, Dolan ME, Cunningham PN
Physiological genomics 2013 Oct 1;45(19):877-88
Physiological genomics 2013 Oct 1;45(19):877-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 14979-1-AP(Galectin 3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-Galectin 3 (IP:14979-1-AP, 3ug; Detection:14979-1-AP 1:500) with MCF-7 cells lysate 1600ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14979-1-AP(Galectin 3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Galectin 3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Galectin 3. This antibody recognizes human,mouse,rat antigen. The Galectin 3 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.