FNab00915

antibody from FineTest Biotech

Targeting: BMP10

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab00915 - Provider product page
Provider: FineTest Biotech
Product name: BMP10 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: bone morphogenetic protein 10
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

BMP10 protein structure - FNab00915 shown in red.