BS6775

antibody from Bioworld Technology, Inc
Targeting: TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
Provider product page for BS6775
Western blot
Immunohistochemistry

Antibody data

Product number
BS6775 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNFRSF14 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TNFRSF14.
Description
HVEM (herpes virus entry mediator A), also known as TR2, ATAR, HVEA, LIGHTR or TNFRSF14 (tumor necrosis factor receptor superfamily, member 14), is a 283 amino acid single-pass type I membrane protein that is widely expressed, with highest expression in lung, spleen and thymus. A member of the TNF receptor superfamily, HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD).HVEM acts as a receptor for two cellular ligands, secreted lymphotoxin and LIGHT. A member of the TNF superfamily produced by activated T-cell, LIGHT is suggested to induce apoptosis and suppress tumor formation. Consisting of three TNFR-Cys repeats, HVEM plays a critical role in HSV pathogenesis. HVEM is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TNFRSF14 protein structure - BS6775 shown in red.