BS60728

antibody from Bioworld Technology, Inc
Targeting: TGFBR3 betaglycan, BGCAN
Provider product page for BS60728

Antibody data

Product number
BS60728 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TGFBR3 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human TGFBR3
Description
A total of three members of the TGFÉÇ family, TGFÉÇ1, TGFÉÇ2 and TGFÉÇ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFÉÇs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFÉÇ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFÉÇ for presentation to signaling receptors.TGFÉÇ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.1.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TGFBR3 protein structure - BS60728 shown in red.