Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 17526-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17526-1-AP, RRID:AB_2219661
- Product name
- ACADL-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ACADL-Specific antibody (Cat. #17526-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction.
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation.
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
Slc22a5 haploinsufficiency does not aggravate the phenotype of the long-chain acyl-CoA dehydrogenase KO mouse.
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function.
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Identification of SPOP related metabolic pathways in prostate cancer.
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Enzogenol improves diabetes-related metabolic change in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus.
Yang J, Zhang Y, Pan Y, Sun C, Liu Z, Liu N, Fu Y, Li X, Li Y, Kong J
Frontiers in cell and developmental biology 2021;9:627135
Frontiers in cell and developmental biology 2021;9:627135
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Guo W, Zhong W, Hao L, Dong H, Sun X, Yue R, Li T, Zhou Z
Cellular and molecular gastroenterology and hepatology 2021;12(5):1599-1615
Cellular and molecular gastroenterology and hepatology 2021;12(5):1599-1615
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
Drake RR, Louey S, Thornburg KL
The Journal of physiology 2021 Nov 21;
The Journal of physiology 2021 Nov 21;
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Ren M, Xu H, Xia H, Tang Q, Bi F
Cell death discovery 2021 May 29;7(1):125
Cell death discovery 2021 May 29;7(1):125
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction.
Tong D, Schiattarella GG, Jiang N, Altamirano F, Szweda PA, Elnwasany A, Lee DI, Yoo H, Kass DA, Szweda LI, Lavandero S, Verdin E, Gillette TG, Hill JA
Circulation research 2021 May 28;128(11):1629-1641
Circulation research 2021 May 28;128(11):1629-1641
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Li Z, Shen W, Wu G, Qin C, Zhang Y, Wang Y, Song G, Xiao C, Zhang X, Deng G, Wang R, Wang X
FEBS open bio 2021 Jul;11(7):1893-1906
FEBS open bio 2021 Jul;11(7):1893-1906
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Kim D, Wu Y, Li Q, Oh YK
Nano-micro letters 2021 Jan 4;13(1):31
Nano-micro letters 2021 Jan 4;13(1):31
Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation.
Fernandes MB, Costa M, Ribeiro MF, Siquenique S, Sá Santos S, Martins J, Coelho AV, Silva MFB, Rodrigues CMP, Solá S
Frontiers in cell and developmental biology 2020;8:335
Frontiers in cell and developmental biology 2020;8:335
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
Lv T, Zhu S, Ma Y, Feng H, Wan Q
Bio-protocol 2020 Sep 20;10(18):e3765
Bio-protocol 2020 Sep 20;10(18):e3765
Slc22a5 haploinsufficiency does not aggravate the phenotype of the long-chain acyl-CoA dehydrogenase KO mouse.
Ranea-Robles P, Yu C, van Vlies N, Vaz FM, Houten SM
Journal of inherited metabolic disease 2020 May;43(3):486-495
Journal of inherited metabolic disease 2020 May;43(3):486-495
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
Riedel EO, Hinrichs A, Kemter E, Dahlhoff M, Backman M, Rathkolb B, Prehn C, Adamski J, Renner S, Blutke A, de Angelis MH, Bidlingmaier M, Schopohl J, Arnold GJ, Fröhlich T, Wolf E
Molecular metabolism 2020 Jun;36:100978
Molecular metabolism 2020 Jun;36:100978
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function.
Thapa D, Manning JR, Mushala BAS, Stoner MW, Zhang M, Scott I
Current research in physiology 2020 Dec;3:44-49
Current research in physiology 2020 Dec;3:44-49
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.
Lv T, Hu Y, Ma Y, Zhen J, Xin W, Wan Q
Journal of physiology and biochemistry 2019 Nov;75(4):597-606
Journal of physiology and biochemistry 2019 Nov;75(4):597-606
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Xu X, Zhu XP, Bai JY, Xia P, Li Y, Lu Y, Li XY, Gao X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7289-7300
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7289-7300
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I
The Journal of biological chemistry 2018 Nov 16;293(46):17676-17684
The Journal of biological chemistry 2018 Nov 16;293(46):17676-17684
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2018 Jan 11;8(1):408
Scientific reports 2018 Jan 11;8(1):408
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Sun Y, Tian Z, Liu N, Zhang L, Gao Z, Sun X, Yu M, Wu J, Yang F, Zhao Y, Ren H, Chen H, Zhao D, Wang Y, Dong S, Xu C, Lu F, Zhang W
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.
Ohashi N, Morino K, Ida S, Sekine O, Lemecha M, Kume S, Park SY, Choi CS, Ugi S, Maegawa H
Diabetes 2017 Sep;66(9):2351-2362
Diabetes 2017 Sep;66(9):2351-2362
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Wu L, Guo X, Lyu Y, Clarke SL, Lucas EA, Smith BJ, Hildebrand D, Wang W, Medeiros DM, Shen X, Lin D
Scientific reports 2017 Nov 7;7(1):14624
Scientific reports 2017 Nov 7;7(1):14624
Identification of SPOP related metabolic pathways in prostate cancer.
Yan M, Qi H, Li J, Ye G, Shao Y, Li T, Liu J, Piao HL, Xu G
Oncotarget 2017 Nov 28;8(61):103032-103046
Oncotarget 2017 Nov 28;8(61):103032-103046
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2017 Aug 21;7(1):8976
Scientific reports 2017 Aug 21;7(1):8976
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
Thapa D, Zhang M, Manning JR, Guimarães DA, Stoner MW, O'Doherty RM, Shiva S, Scott I
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H265-H274
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H265-H274
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Huang, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P, Zhang H
Cell reports 2014 Sep 25;8(6):1930-1942
Cell reports 2014 Sep 25;8(6):1930-1942
Enzogenol improves diabetes-related metabolic change in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus.
Bang CY, Choung SY
The Journal of pharmacy and pharmacology 2014 Jun;66(6):875-85
The Journal of pharmacy and pharmacology 2014 Jun;66(6):875-85
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 17526-1-AP(ACADL-Specific antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACADL-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ACADL-Specific. This antibody recognizes human,mouse,rat antigen. The ACADL-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.