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Cell line expression
Protein structure
VAC14
VAC14 component of PIKFYVE complexArPIKfyve, FLJ10305, TAX1BP2
This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. [provided by RefSeq, May 2017]
Top validated antibodies |
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| Proteintech Group |  15771-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
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| LSBio | LS-C392896 |
Polyclonal |
WB
IHC
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| Invitrogen Antibodies | 15771-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| NovoPro Bioscience Inc. | 116702 |
Polyclonal |
WB
EL
IP
IHC
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| FineTest Biotech | FNab09356 |
Polyclonal |
WB
EL
IP
IHC
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