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Protein structure
LRBA
LPS responsive beige-like anchor proteinBGL, CDC4L, LAB300, LBA
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Top validated antibodies |
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| Atlas Antibodies |  HPA019366 |
1 references | Polyclonal |
ICC
IHC
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| Biorbyt | orb451254 |
Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NBP1-90765 |
1 references | Polyclonal |
ICC
IHC
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| LSBio | LS-C285555 |
Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA013070LA01HU |
Polyclonal |
EL
ICC
IHC
|
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