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LearnMAB3231
antibody from Abnova Corporation
Targeting: CD40LG
CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- MAB3231 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB3231, RRID:AB_10628931
- Product name
- Cd40lg monoclonal antibody, clone MR1
- Antibody type
- Monoclonal
- Description
- Hamster monoclonal antibody raised against Cd40lg.
- Isotype
- IgG
- Antibody clone number
- MR1
- Storage
- Store at 4°C.
Submitted references An essential role for gp39, the ligand for CD40, in thymic selection.
In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.
Foy TM, Page DM, Waldschmidt TJ, Schoneveld A, Laman JD, Masters SR, Tygrett L, Ledbetter JA, Aruffo A, Claassen E, Xu JC, Flavell RA, Oehen S, Hedrick SM, Noelle RJ
The Journal of experimental medicine 1995 Nov 1;182(5):1377-88
The Journal of experimental medicine 1995 Nov 1;182(5):1377-88
In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.
Foy TM, Shepherd DM, Durie FH, Aruffo A, Ledbetter JA, Noelle RJ
The Journal of experimental medicine 1993 Nov 1;178(5):1567-75
The Journal of experimental medicine 1993 Nov 1;178(5):1567-75
The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.
Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, Bajorath J, Grosmaire LS, Stenkamp R, Neubauer M
Cell 1993 Jan 29;72(2):291-300
Cell 1993 Jan 29;72(2):291-300
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Partially purified spleen T cells from BALB/c mice were incubated with either hamster IgG or plate-bound Cd3e monoclonal antibody, clone 145-2C11 for 7 hours at 37°C. The cells were then harvested, double-stained with Cd40lg monoclonal antibody, clone MR1 (Cat # MAB3231)-FITC and anti-CD4+8-R-PE, and analyzed by flow cytometry.
- Validation comment
- Flow Cytometry
