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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4573 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4573, RRID:AB_1578843
- Product name
- PKLR polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PKLR.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians.
PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations.
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.
Wang H, Chu W, Das SK, Ren Q, Hasstedt SJ, Elbein SC
Diabetes 2002 Sep;51(9):2861-5
Diabetes 2002 Sep;51(9):2861-5
PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations.
Mateu E, Pérez-Lezaun A, Martínez-Arias R, Andrés A, Vallés M, Bertranpetit J, Calafell F
Human genetics 2002 Jun;110(6):532-44
Human genetics 2002 Jun;110(6):532-44
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.
Valentini G, Chiarelli LR, Fortin R, Dolzan M, Galizzi A, Abraham DJ, Wang C, Bianchi P, Zanella A, Mattevi A
The Journal of biological chemistry 2002 Jun 28;277(26):23807-14
The Journal of biological chemistry 2002 Jun 28;277(26):23807-14
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PKLR polyclonal antibody (Cat # PAB4573) is used in Western blot to detect PKLR in mouse liver tissue lysate .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PKLR polyclonal antibody (Cat # PAB4573) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
