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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
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- Product number
- PAB6747 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB6747, RRID:AB_1570857
- Product name
- ACHE polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Goat polyclonal antibody raised against synthetic peptide of ACHE.
- Antigen sequence
QFDHYSKQDRCSDL- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Cholinergic imbalance in the multiple sclerosis hippocampus.
The intact human acetylcholinesterase C-terminal oligomerization domain is alpha-helical in situ and in isolation, but a shorter fragment forms beta-sheet-rich amyloid fibrils and protofibrillar oligomers.
Kooi EJ, Prins M, Bajic N, Beliën JA, Gerritsen WH, van Horssen J, Aronica E, van Dam AM, Hoozemans JJ, Francis PT, van der Valk P, Geurts JJ
Acta neuropathologica 2011 Sep;122(3):313-22
Acta neuropathologica 2011 Sep;122(3):313-22
The intact human acetylcholinesterase C-terminal oligomerization domain is alpha-helical in situ and in isolation, but a shorter fragment forms beta-sheet-rich amyloid fibrils and protofibrillar oligomers.
Cottingham MG, Voskuil JL, Vaux DJ
Biochemistry 2003 Sep 16;42(36):10863-73
Biochemistry 2003 Sep 16;42(36):10863-73
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- ACHE polyclonal antibody (Cat # PAB6747) (0.3 ug/mL) staining of human brain (Hippocampus) lysate (35 ug protein in RIPA buffer) with (A) and without (B) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
