Tissue expression
Cell line expression
Protein structure
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3LH3
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 11027-1-AP | 33 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 11027-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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NovoPro Bioscience Inc. | 107477 | Monoclonal |
WB
EL
ICC
IP
IHC
|
||
FineTest Biotech | FNab06553 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Biorbyt | orb395457 | Monoclonal |
WB
EL
ICC
IP
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider