Tissue expression
Cell line expression
Protein structure
TPCN2
Two pore segment channel 2TPC2
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation. [provided by RefSeq, Dec 2009]
Top validated antibodies |
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Novus Biologicals | NBP1-45234 | 1 references | Polyclonal |
WB
EL
IHC
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Invitrogen Antibodies | ACC-072-200UL | Polyclonal |
WB
ICC
IHC
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OriGene | TA328756 | Polyclonal |
WB
ICC
IHC
|
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LSBio | LS-C95186 | Polyclonal |
WB
IHC |
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Atlas Antibodies | HPA027080 | Polyclonal |
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider