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- Product number
- ABIN396706 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-S100 Calcium Binding Protein A6 (S100A6) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 6D1
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references S100 proteins interact with the N-terminal domain of MDM2.
Increased cytoplasmic S100A6 expression is associated with pulmonary adenocarcinoma progression.
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility.
Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients.
Proteomic profiling in distinct cellular compartments of tumor cells reveals p53-dependent upregulation of S100A6 upon induction of telomere dysfunction.
van Dieck J, Lum JK, Teufel DP, Fersht AR
FEBS letters 2010 Aug 4;584(15):3269-74
FEBS letters 2010 Aug 4;584(15):3269-74
Increased cytoplasmic S100A6 expression is associated with pulmonary adenocarcinoma progression.
Ishii A, Suzuki M, Satomi K, Kobayashi H, Sakashita S, Kano J, Pei Y, Minami Y, Ishikawa S, Noguchi M
Pathology international 2009 Sep;59(9):623-30
Pathology international 2009 Sep;59(9):623-30
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility.
Nedjadi T, Kitteringham N, Campbell F, Jenkins RE, Park BK, Navarro P, Ashcroft F, Tepikin A, Neoptolemos JP, Costello E
British journal of cancer 2009 Oct 6;101(7):1145-54
British journal of cancer 2009 Oct 6;101(7):1145-54
Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients.
Wei BR, Hoover SB, Ross MM, Zhou W, Meani F, Edwards JB, Spehalski EI, Risinger JI, Alvord WG, Quiñones OA, Belluco C, Martella L, Campagnutta E, Ravaggi A, Dai RM, Goldsmith PK, Woolard KD, Pecorelli S, Liotta LA, Petricoin EF, Simpson RM
PloS one 2009 Oct 30;4(10):e7670
PloS one 2009 Oct 30;4(10):e7670
Proteomic profiling in distinct cellular compartments of tumor cells reveals p53-dependent upregulation of S100A6 upon induction of telomere dysfunction.
Zimmermann S, Biniossek ML, Maurer C, Münzer P, Pantic M, Veelken H, Martens UM
Proteomics 2009 Nov;9(22):5175-87
Proteomics 2009 Nov;9(22):5175-87
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- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
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- ELISA
