Antibody data

Product number
PA1-24423 - Provider product page
Provider
Invitrogen Antibodies
Product name
GAS41 Polyclonal Antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide
Description
Description: The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
50 µg
Concentration
0.5 mg/mL
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
YEATS4 protein structure - PA1-24423 shown in red.