FNab01285

antibody from FineTest Biotech

Targeting: CASP10 FLICE-2, MCH4

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ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

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Validation data

Product number: FNab01285 - Provider product page
Provider: FineTest Biotech
Product name: Caspase 10 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: caspase 10, apoptosis-related cyste ine peptidase
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CASP10 protein structure - FNab01285 shown in red.