BS8444

antibody from Bioworld Technology, Inc
Targeting: YARS1 tyrRS, YARS, YRS, YTS
Provider product page for BS8444
Western blot
Immunohistochemistry

Antibody data

Product number
BS8444 - Provider product page
Provider
Bioworld Technology, Inc
Product name
YARS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human YARS.
Description
Tryptophanyl-tRNA synthetases are essential enzymes that catalyze the aminoacylation of tRNA(Trp) with tryptophan, an essential function of the cell£ªs protein synthesis machinery. Two forms of tryptophanyl-tRNA synthetase exist; a cytoplasmic form, named TrpRS (also known as WARS), and a mitochondrial form, named WARS2. In normal cells, human TrpRS exists as a full length form and as a truncated form designated mini TrpRS, which is produced by alternative splicing. Expression of mini TrpRS is highly stimulated in human cells by the addition of IFN-g. Although both human full length TrpRS and mini TrpRS are enzymatically active in aminoacylation, they differ in angiostatic activity. The tyrosyl-tRNA synthetase (TyrRS), a protein related to TrpRS, exists as a homodimeric enzyme that catalyzes the aminoacylation of tRNA(Tyr) by L-tyrosine.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
YARS1 protein structure - BS8444 shown in red.