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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Western blot [2]
- ELISA [1]
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- Product number
- H00008565-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00008565-M02, RRID:AB_2304790
- Product name
- Mouse Monoclonal YARS Antibody
- Antibody type
- Monoclonal
- Description
- Ascites. YARS - tyrosyl-tRNA synthetase (2F3)
- Reactivity
- Human, Mouse, Drosophila
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases.
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy.
Niehues S, Bussmann J, Steffes G, Erdmann I, Köhrer C, Sun L, Wagner M, Schäfer K, Wang G, Koerdt SN, Stum M, Jaiswal S, RajBhandary UL, Thomas U, Aberle H, Burgess RW, Yang XL, Dieterich D, Storkebaum E
Nature communications 2015 Jul 3;6:7520
Nature communications 2015 Jul 3;6:7520
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy.
Storkebaum E, Leitão-Gonçalves R, Godenschwege T, Nangle L, Mejia M, Bosmans I, Ooms T, Jacobs A, Van Dijck P, Yang XL, Schimmel P, Norga K, Timmerman V, Callaerts P, Jordanova A
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 14;106(28):11782-7
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 14;106(28):11782-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: YARS Antibody (2F3) [H00008565-M02] - Analysis of YARS expression in NIH/3T3 (Cat # L018V1).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: YARS Antibody (2F3) [H00008565-M02] - Analysis of YARS expression in HeLa (Cat # L013V1).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: YARS Antibody (2F3) [H00008565-M02] - Detection limit for recombinant GST tagged YARS is 0.1 ng/ml as a capture antibody.
