PRSS21

This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Description

Serine protease 21

Tissue specificity

Tissue enriched (testis)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (2817180 - 2826304)

Ensembl ID

ENSG00000007038  (ver. 103.38)

Orthologs

Mouse Prss21: ENSMUSG00000024116

UniProt

Q9Y6M0

neXtProt

NX_Q9Y6M0

Human splice variants
Mouse splice variants

Protein structure