FNab09339

antibody from FineTest Biotech
Targeting: USP5 IsoT
Provider product page for FNab09339
Western blot
ELISA
Immunoprecipitation

Antibody data

Product number
FNab09339 - Provider product page
Provider
FineTest Biotech
Product name
USP5 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
ubiquitin specific peptidase 5(isop
eptidase T)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
USP5 protein structure - FNab09339 shown in red.