Tissue expression
Cell line expression
Protein structure
PI3
Peptidase inhibitor 3cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]
Top validated antibodies |
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R&D Systems | ![]() |
3 references | Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
4 references | Polyclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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