Tissue expression
Cell line expression
Protein structure
MXD3
MAX dimerization protein 3bHLHc13, MAD3
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Biorbyt | ![]() |
Recombinant |
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antibodies-online | ![]() |
4 references | Polyclonal |
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St John's Laboratory | ![]() |
Polyclonal |
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Antibodies.com | ![]() |
Polyclonal |
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