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Learn12143-1-AP
antibody from Proteintech Group
Targeting: TP63
EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12143-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12143-1-AP, RRID:AB_10597397
- Product name
- p63 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated p63 antibody (Cat. #12143-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Midterm outcomes of penetrating keratoplasty following allogeneic cultivated limbal epithelial transplantation in patients with bilateral limbal stem cell deficiency.
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro.
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
Genome-Wide Identification of Autophagy Prognostic Signature in Pancreatic Cancer.
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
CEBPG promotes esophageal squamous cell carcinoma progression by enhancing PI3K-AKT signaling.
Tmub1 Suppresses Hepatocellular Carcinoma by Promoting the Ubiquitination of ΔNp63 Isoforms.
Protective Effects of Dietary Grape on UVB-Mediated Cutaneous Damages and Skin Tumorigenesis in SKH-1 Mice.
Chloride channels regulate differentiation and barrier functions of the mammalian airway.
Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model.
ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia.
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.
NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes.
Molecular pathogenesis of human prostate basal cell hyperplasia.
All-trans-retinoid acid (ATRA) suppresses chondrogenesis of rat primary hind limb bud mesenchymal cells by downregulating p63 and cartilage-specific molecules.
Xue JF, Li DF, Wang YN, Chen C, Yang RF, Zhou QJ, Liu T, Xie LX, Dong YL
International journal of ophthalmology 2021;14(11):1690-1699
International journal of ophthalmology 2021;14(11):1690-1699
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro.
Li CY, Chen CY, An JH, Wu JB, Shen H
Cancer management and research 2021;13:3685-3697
Cancer management and research 2021;13:3685-3697
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Wu J, Wu T, Zheng S, Huang Y, Wang L
Experimental eye research 2021 Sep;210:108696
Experimental eye research 2021 Sep;210:108696
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
Huang Y, Yang Q, Zheng Y, Lin L, Xu X, Xu XE, Silva TC, Hazawa M, Peng L, Cao H, Ding Y, Lu D, Berman BP, Xu LY, Li EM, Yin D
Nucleic acids research 2021 Sep 20;49(16):9246-9263
Nucleic acids research 2021 Sep 20;49(16):9246-9263
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells.
Manna V, Caradonna S
STAR protocols 2021 Dec 17;2(4):100782
STAR protocols 2021 Dec 17;2(4):100782
Genome-Wide Identification of Autophagy Prognostic Signature in Pancreatic Cancer.
Yu J, Lang Q, Zhong C, Wang S, Tian Y
Dose-response : a publication of International Hormesis Society 2021 Apr-Jun;19(2):15593258211023260
Dose-response : a publication of International Hormesis Society 2021 Apr-Jun;19(2):15593258211023260
ΔNp63α promotes the expression and nuclear translocation of PTEN, leading to cisplatin resistance in oral cancer cells.
Hao T, Gan YH
American journal of translational research 2020;12(10):6187-6203
American journal of translational research 2020;12(10):6187-6203
CEBPG promotes esophageal squamous cell carcinoma progression by enhancing PI3K-AKT signaling.
Huang Y, Lin L, Shen Z, Li Y, Cao H, Peng L, Qiu Y, Cheng X, Meng M, Lu D, Yin D
American journal of cancer research 2020;10(10):3328-3344
American journal of cancer research 2020;10(10):3328-3344
Tmub1 Suppresses Hepatocellular Carcinoma by Promoting the Ubiquitination of ΔNp63 Isoforms.
Fu H, Zhang Y, Chen J, Zhou B, Chen G, Chen P
Molecular therapy oncolytics 2020 Sep 25;18:126-136
Molecular therapy oncolytics 2020 Sep 25;18:126-136
Protective Effects of Dietary Grape on UVB-Mediated Cutaneous Damages and Skin Tumorigenesis in SKH-1 Mice.
Mintie CA, Musarra AK, Singh CK, Ndiaye MA, Sullivan R, Eickhoff JC, Ahmad N
Cancers 2020 Jul 1;12(7)
Cancers 2020 Jul 1;12(7)
Chloride channels regulate differentiation and barrier functions of the mammalian airway.
He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY
eLife 2020 Apr 14;9
eLife 2020 Apr 14;9
Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model.
Wang S, Wang N, Yu B, Cao M, Wang Y, Guo Y, Zhang Y, Zhang P, Yu X, Wang S, Zeng L, Liang B, Li X, Wu Y
Oncogene 2019 Sep;38(36):6338-6353
Oncogene 2019 Sep;38(36):6338-6353
ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia.
Haas M, Gómez Vázquez JL, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Cell reports 2019 Sep 24;28(13):3338-3352.e6
Cell reports 2019 Sep 24;28(13):3338-3352.e6
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Hu L, Pu Q, Zhang Y, Ma Q, Li G, Li X
Experimental eye research 2019 May;182:44-56
Experimental eye research 2019 May;182:44-56
Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.
Diaz-Flores E, Comeaux EQ, Kim KL, Melnik E, Beckman K, Davis KL, Wu K, Akutagawa J, Bridges O, Marino R, Wohlfeil M, Braun BS, Mullighan CG, Loh ML
Cancer research 2019 May 1;79(9):2339-2351
Cancer research 2019 May 1;79(9):2339-2351
NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes.
Wu X, Yang B, Hu Y, Sun R, Wang H, Fu J, Hou Y, Pi J, Xu Y
Oxidative medicine and cellular longevity 2017;2017:7417694
Oxidative medicine and cellular longevity 2017;2017:7417694
Molecular pathogenesis of human prostate basal cell hyperplasia.
Henry G, Malewska A, Mauck R, Gahan J, Hutchinson R, Torrealba J, Francis F, Roehrborn C, Strand D
The Prostate 2017 May;77(13):1344-1355
The Prostate 2017 May;77(13):1344-1355
All-trans-retinoid acid (ATRA) suppresses chondrogenesis of rat primary hind limb bud mesenchymal cells by downregulating p63 and cartilage-specific molecules.
Wang YG, Xie P, Wang YG, Li XD, Zhang TG, Liu ZY, Hong Q, Du SX
Environmental toxicology and pharmacology 2014 Sep;38(2):460-8
Environmental toxicology and pharmacology 2014 Sep;38(2):460-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The p63 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human p63. This antibody recognizes human,mouse,rat antigen. The p63 antibody has been validated for the following applications: ELISA, WB analysis.
