Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 10208-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10208-1-AP, RRID:AB_2095834
- Product name
- EFTUD2 antibody
- Antibody type
- Polyclonal
- Description
- EFTUD2 antibody (Cat. #10208-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer.
A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells.
Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.
XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.
Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
Reduced prostaglandin I(2) signaling in Arid5b(-/-) primary skeletal muscle cells attenuates myogenesis.
Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.
A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups.
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Knockdown of AT-rich interaction domain (ARID) 5B gene expression induced AMPKα2 activation in cardiac myocytes.
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.
Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.
Zhu X, Li C, Gao Y, Zhang Q, Wang T, Zhou H, Bu F, Chen J, Mao X, He Y, Wu K, Li N, Luo H
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):7
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):7
A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells.
Ceccacci S, Corsi L, Spinelli L, Caroli C, Marani M, Anceschi L, Mozzicafreddo M, Pellati F, Monti MC
Heliyon 2024 Jan 15;10(1):e24196
Heliyon 2024 Jan 15;10(1):e24196
Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.
Yu NK, McClatchy DB, Diedrich JK, Romero S, Choi JH, Martínez-Bartolomé S, Delahunty CM, Muotri AR, Yates JR 3rd
iScience 2021 Nov 19;24(11):103321
iScience 2021 Nov 19;24(11):103321
XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.
Hou S, Qu D, Li Y, Zhu B, Liang D, Wei X, Tang W, Zhang Q, Hao J, Guo W, Wang W, Zhao S, Wang Q, Azam S, Khan M, Zhao H, Zhang L, Lei H
Nucleic acids research 2019 Sep 5;47(15):8239-8254
Nucleic acids research 2019 Sep 5;47(15):8239-8254
Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.
Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B
Nature immunology 2019 Oct;20(10):1322-1334
Nature immunology 2019 Oct;20(10):1322-1334
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
Jiao AL, Perales R, Umbreit NT, Haswell JR, Piper ME, Adams BD, Pellman D, Kennedy S, Slack FJ
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
Reduced prostaglandin I(2) signaling in Arid5b(-/-) primary skeletal muscle cells attenuates myogenesis.
Murray J, Whitson RH, Itakura K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Apr;32(4):1868-1879
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Apr;32(4):1868-1879
Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.
Chen Z, Gui B, Zhang Y, Xie G, Li W, Liu S, Xu B, Wu C, He L, Yang J, Yi X, Yang X, Sun L, Liang J, Shang Y
The Journal of biological chemistry 2017 Nov 3;292(44):18113-18128
The Journal of biological chemistry 2017 Nov 3;292(44):18113-18128
A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups.
Jang MK, Anderson DE, van Doorslaer K, McBride AA
Proteomics 2015 Jun;15(12):2038-50
Proteomics 2015 Jun;15(12):2038-50
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Szerlong HJ, Herman JA, Krause CM, DeLuca JG, Skoultchi A, Winger QA, Prenni JE, Hansen JC
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Knockdown of AT-rich interaction domain (ARID) 5B gene expression induced AMPKα2 activation in cardiac myocytes.
Hirose-Yotsuya L, Okamoto F, Yamakawa T, Whitson RH, Fujita-Yamaguchi Y, Itakura K
Bioscience trends 2015 Dec;9(6):377-85
Bioscience trends 2015 Dec;9(6):377-85
New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.
Huang R, Yu M, Li CY, Zhan YQ, Xu WX, Xu F, Ge CH, Li W, Yang XM
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
Proteomics. Clinical applications 2012 Oct;6(9-10):467-75
A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.
Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G
Molecular and cellular biology 2012 Apr;32(7):1271-83
Molecular and cellular biology 2012 Apr;32(7):1271-83
Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.
Murray J, Huss JM
American journal of physiology. Cell physiology 2011 Sep;301(3):C630-45
American journal of physiology. Cell physiology 2011 Sep;301(3):C630-45
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10208-1-AP(EFTUD2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using EFTUD2 antibody 10208-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-EFTUD2 (IP:10208-1-AP, 3ug; Detection:10208-1-AP 1:1000) with HeLa cells lysate 4650ug.
- Sample type
- cell line