FNab09334

antibody from FineTest Biotech

Targeting: USP44 FLJ14528

Western blot

ELISA

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Validation data

Product number: FNab09334 - Provider product page
Provider: FineTest Biotech
Product name: USP44 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ubiquitin specific peptidase 44
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

USP44 protein structure - FNab09334 shown in red.