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Protein structure
POU6F2
POU class 6 homeobox 2RPF-1
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| antibodies-online |  ABIN954262 |
4 references | Polyclonal |
WB
EL
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| Novus Biologicals | NBP1-52038 |
1 references | Polyclonal |
WB
EL
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| Cusabio Biotech Co., Ltd | CSB-PA571782 |
Polyclonal |
WB
EL
IHC
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| LSBio | LS-C113014 |
Polyclonal |
WB
EL
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| Biorbyt | orb524776 |
Polyclonal |
WB
EL
IHC
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